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Third-Party HPLC Tested HPLC Tested
Accurately measure your Thymosin Beta-4 Fragment tissue repair protocols. Enter your vial size, bacteriostatic water volume, and desired dose to calculate the exact syringe draw.
Standard TB-500 vials are typically 2mg, 5mg, or 10mg.
Volume of water used to reconstitute the lyophilized powder.
TB-500 is typically dosed in milligrams (e.g., 2.0mg, 2.5mg).
Select the maximum capacity of your U-100 insulin syringe.
Draw exactly to the 100 unit mark (red line) on a 1mL (100 Unit) insulin syringe.
Concentration
2.50 mg/mL
Dose per Unit (1/100 mL)
25.0 mcg/Unit
Volume to Inject
1.00 mL
Select a TB-500 research protocol below to view its specific dosing schedule.
| Phase | Timeline | Dosage & Frequency |
|---|---|---|
| Loading Phase | Weeks 1 - 2 | 5.0 - 7.0 mg / week (Split in 2-3 injections) |
| Active Repair | Weeks 3 - 6 | 2.5 - 5.0 mg / week (Split in 2 injections) |
| Taper/Maintenance | Weeks 7 - 8 | 2.0 mg / week (1 injection) |
| Resolution | Week 9+ | Discontinue |
Aggressive front-loading phase is utilized to rapidly saturate actin-binding proteins and stimulate immediate cell migration to the localized injury site.
Thymosin Beta-4 Fragment
A synthetic version of a naturally occurring peptide used primarily for muscle tear repair, reducing inflammation, and increasing flexibility.
TB-500 is a synthetic fraction of the naturally occurring protein Thymosin Beta-4. Its primary mechanism of action is the up-regulation of Actin—a crucial cell-building protein.
By binding to and sequestering actin, TB-500 promotes cell migration and proliferation. It essentially instructs the body to build new cellular structures, while simultaneously encouraging angiogenesis (new blood vessel formation) to feed the repairing tissue.
Result: Rapid healing of muscle tissue tears, restoration of lost flexibility via scar tissue reduction, and profound systemic anti-inflammatory effects.
Like all lyophilized peptides, TB-500 is fragile in its powder state. Store unmixed vials in the freezer (-20°C). Once reconstituted with Bacteriostatic Water, the peptide must be refrigerated (2°C - 8°C).
TB-500 is notable for having a relatively long biological half-life for a tissue-repair peptide, typically active in the system for 7 to 10 days.
Because of this extended half-life, systemic saturation is easily achieved with infrequent dosing. Unlike BPC-157 which requires daily injections, TB-500 protocols traditionally only require 1 to 2 injections per week to maintain optimal healing concentrations.
TB-500 encourages the proliferation of cells and new blood vessel formation. Therefore, it should be strictly avoided in subjects with active cancers or highly proliferative tumor diseases.
Caution: While TB-500 itself is not carcinogenic, its potent mechanisms of cellular growth and angiogenesis can theoretically supply increased resources to pre-existing malignant cells.